Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730954 | 0.94 | SMN1; SMN2 (0.49) | SMN1; SMN2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL21965755 | 0.92 | SMN1; SMN2 (0.51) | SMN1; SMN2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL19121210 | 0.87 | TRPA1 (0.44) | SMN1; SMN2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL15690948 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6085223 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27489390 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2HDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL11935645 | 0.78 | ACHE (0.41) | ALDH1A1KDM4E | |
| SCHEMBL19673827 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL7288546 | 0.77 | ELANE (0.45) | SMN1; SMN2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL11660041 | 0.76 | TRPA1 (0.43) | SMN1; SMN2MEN1KMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724322-B | Androgen receptor modulators and uses thereof | 亚拉冈制药公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-102884057-B | Androgen receptor modulators and uses thereof | 亚拉冈制药公司 | 2016-09-14 | — | — | CN | disclosed |