Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.73 |
| ▸ | DRD4 | P21917 | 4/20 | 0.73 |
| ▸ | DRD3 | P35462 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231185 | 0.94 | DRD2 (0.76) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL20234658 | 0.94 | DRD2 (0.76) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL27465 | 0.92 | DRD2 (0.62) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL29381067 | 0.92 | DRD2 (0.62) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL5686017 | 0.90 | DRD2 (0.72) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL2063136 | 0.90 | DRD2 (0.72) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL1930661 | 0.89 | ACHE (0.64) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL17561648 | 0.88 | DRD2 (0.63) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL10707296 | 0.87 | L3MBTL1 (0.61) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL5289703 | 0.87 | DRD2 (0.58) | DRD2DRD4DRD3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645396-B2 | 1,2-bis(3-methylphenoxy)ethane composition and thermal recording media made by using the same | SANKO CO., LTD. (JP) | 2010-01-12 | — | — | US | claimed |
| US-7566682-B2 | 1,2-bis(3-methylphenoxy)ethane composition and thermal recording media made by using the same | SANKO CO., LTD (JP) | 2009-07-28 | — | — | US | claimed |
| US-20090166594-A1 | 1,2-BIS(3-METHYLPHENOXY)ETHANE COMPOSITION AND THERMAL RECORDING MEDIA MADE BY USING THE SAME | SANKO CO., LTD. (JP) | 2009-07-02 | — | — | US | claimed |
| CN-100379580-C | 1, 2-bis (3-methylphenoxy) ethane composition and thermal recording medium prepared by using the same | SANKO CO LTD (JP) | 2008-04-09 | — | — | CN | claimed |
| US-20070111887-A1 | 1,2-Bis(3-methylphenoxy)ethane composition and thermal recording media made by using the same | SANKO CO., LTD. (JP) | 2007-05-17 | — | — | US | claimed |
| EP-1595714-B1 | 1,2-BIS(3-METHYLPHENOXY)ETHANE COMPOSITION AND THERMAL RECORDING MEDIA MADE BY USING THE SAME | SANKO CO LTD (JP) | 2007-04-11 | — | — | EP | claimed |
| CN-1750939-A | 1, 2-bis (3-methylphenoxy) ethane composition and thermal recording medium prepared by using the same | SANKO CO LTD (JP) | 2006-03-22 | — | — | CN | claimed |
| EP-1595714-A1 | 1,2-BIS(3-METHYLPHENOXY)ETHANE COMPOSITION AND THERMAL RECORDING MEDIA MADE BY USING THE SAME | Sanko Co., Ltd. (JP) | 2005-11-16 | — | — | EP | claimed |
| JP-4010978-A | — | — | None | — | — | JP | disclosed |
| US-10501413-B2 | Inhibitors of the Notch transcriptional activation complex and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2019-12-10 | — | — | US | disclosed |
| US-20180086700-A1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-29 | — | — | US | disclosed |
| CN-102712202-B | Thermosensitive type lithographic plate and printing process thereof | MITSUBISHI PAPER MILLS LTD. (JP) | 2015-10-21 | — | — | CN | disclosed |
| US-8978553-B2 | Heat-sensitive lithographic printing plates | MITSUBISHI PAPER MILLS LIMITED (JP) | 2015-03-17 | — | — | US | disclosed |
| CN-102712202-A | Heat-sensitive lithographic printing plate and printing method thereof | MITSUBISHI PAPER MILLS LTD | 2012-10-03 | — | — | CN | disclosed |
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4833121-A | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0141170-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| US-4659643-A | A PHENOXY COMPOUND | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4531140-A | Heat-sensitive recording material | Kansaki Paper Manufacturing Co. Ltd. (JP) | 1985-07-23 | — | — | US | disclosed |
| EP-0141170-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10501413-B2 | Inhibitors of the Notch transcriptional activation complex and methods for use of the same | NOTCH1, CBFB, HES1 | DRD2 4804/4885DRD4 4764/4885DRD3 4789/4885 |
| US-20180086700-A1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME | NOTCH1, CBFB, HES1 | DRD2 4804/4885DRD4 4764/4885DRD3 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.