Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934639 | 0.82 | SCN9A (0.38) | — | |
| SCHEMBL30740989 | 0.82 | SCN9A (0.38) | — | |
| SCHEMBL29344589 | 0.80 | FABP7 (0.31) | FABP7FABP3FABP5 | |
| SCHEMBL2760211 | 0.77 | KCNH2 (0.37) | FABP7FABP3FABP5 | |
| Methylamine SCHEMBL27640156 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL28777064 | 0.76 | SLC22A12 (0.38) | FABP5 | |
| SCHEMBL10886037 | 0.76 | KMT2A (0.42) | — | |
| SCHEMBL10922102 | 0.76 | HSD11B1 (0.33) | — | |
| SCHEMBL10922032 | 0.76 | PPARG (0.40) | — | |
| SCHEMBL29344700 | 0.75 | FABP7 (0.33) | FABP7FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334529-B | Compounds and compositions for inhibiting the activity of ABL1, ABL2, and BCR-ABL1 | 诺华股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-104379574-B | For suppressing the heterocyclic carbamate derivatives of the activity of ABL1, ABL2 and BCR ABL1 | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-104302634-B | Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1 | 诺华股份有限公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-104302638-B | BENZAMIDE DERIVATIVES FOR INHIBITING THE ACTIVITY OF ABL1, ABL2 AND BCR-ABL1 | 诺华股份有限公司 | 2016-08-24 | — | — | CN | disclosed |