Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240578 | 0.77 | ALOX15 (0.55) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27965972 | 0.73 | ALDH1A1 (0.58) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27859886 | 0.73 | GAA (0.50) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28119079 | 0.72 | SRC (0.32) | — | |
| SCHEMBL28104481 | 0.72 | SRC (0.38) | GAAALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL12085215 | 0.71 | MAPT (0.59) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16750169 | 0.70 | GAA (0.54) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28097289 | 0.70 | SRC (0.36) | — | |
| SCHEMBL28104478 | 0.70 | GAA (0.43) | GAAALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL28119035 | 0.70 | MAOA (0.42) | ALDH1A1MAPTIKBKBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958521-B | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | 弗·哈夫曼-拉罗切有限公司 | 2016-10-19 | — | — | CN | disclosed |