Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975011 | 0.84 | AGBL2 (0.33) | AGBL2S1PR1S1PR3AAK1 | |
| SCHEMBL28203424 | 0.80 | HTT (0.36) | — | |
| SCHEMBL17841682 | 0.79 | AGXT (0.35) | AGBL2S1PR1S1PR3AAK1HSD17B10 | |
| SCHEMBL28329140 | 0.76 | EGLN2 (0.34) | — | |
| SCHEMBL25283521 | 0.75 | PTGDR2 (0.33) | AGBL2S1PR1S1PR3AAK1HSD17B10 | |
| SCHEMBL5734033 | 0.75 | AGBL2 (0.37) | AGBL2AAK1HSD17B10 | |
| SCHEMBL15080876 | 0.72 | S1PR1 (0.37) | AGBL2S1PR1S1PR3HSD17B10SMN1; SMN2 | |
| SCHEMBL29338673 | 0.72 | S1PR1 (0.37) | AGBL2S1PR1S1PR3AAK1HSD17B10 | |
| SCHEMBL1577309 | 0.71 | AAK1 (0.32) | S1PR1S1PR3AAK1 | |
| SCHEMBL2112705 | 0.71 | S1PR1 (0.39) | AGBL2S1PR1S1PR3HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958521-B | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | 弗·哈夫曼-拉罗切有限公司 | 2016-10-19 | — | — | CN | disclosed |