Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393653 | 0.83 | AGBL2 (0.39) | AGBL2ALDH1A1ELANEKDM4EHSD17B10 | |
| SCHEMBL31691297 | 0.83 | ALDH1A1 (0.35) | AGBL2ALDH1A1CA2CYP3A4 | |
| SCHEMBL2067833 | 0.83 | NOTUM (0.37) | ALDH1A1CA2MEN1KMT2AKDM4E | |
| SCHEMBL2067188 | 0.81 | NPC1 (0.37) | ALDH1A1MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL29333332 | 0.79 | SSTR4 (0.39) | AGBL2ALDH1A1CA2MEN1KMT2A | |
| SCHEMBL30994666 | 0.79 | SSTR4 (0.39) | AGBL2ALDH1A1CA2MEN1KMT2A | |
| SCHEMBL17841682 | 0.78 | AGXT (0.35) | AGBL2AAK1KMT2AKDM4EHSD17B10 | |
| SCHEMBL3392712 | 0.77 | CA2 (0.38) | AGBL2ALDH1A1PKMCA2ELANE | |
| SCHEMBL29333320 | 0.77 | L3MBTL1 (0.41) | ALDH1A1CA2KMT2ALMNAPOLB | |
| SCHEMBL28097366 | 0.75 | AGBL2 (0.32) | AGBL2AAK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |