Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703585 | 0.91 | SLC6A4 (0.67) | MAPTSLC6A4OPRM1OPRK1LMNA | |
| SCHEMBL16801678 | 0.89 | SLC6A4 (0.56) | MAPTSLC6A4OPRM1OPRK1LMNA | |
| SCHEMBL28097370 | 0.86 | TDO2 (0.65) | MAPTSLC6A4LMNAHTR1DTDO2 | |
| SCHEMBL31385885 | 0.86 | MAPT (0.57) | MAPTSLC6A4LMNATDO2POLB | |
| SCHEMBL6383779 | 0.84 | CNR1 (0.57) | MAPTSLC6A4OPRM1OPRK1LMNA | |
| SCHEMBL28097296 | 0.83 | LMNA (0.64) | MAPTSLC6A4LMNATDO2POLB | |
| SCHEMBL7219966 | 0.82 | MAPT (0.51) | MAPTSLC6A4OPRM1OPRK1LMNA | |
| SCHEMBL22491445 | 0.81 | MAPT (0.56) | MAPTSLC6A4OPRM1OPRK1LMNA | |
| SCHEMBL4670751 | 0.80 | SLC6A4 (0.81) | SLC6A4LMNAPOLB | |
| SCHEMBL16801734 | 0.80 | SLC6A4 (0.69) | MAPTSLC6A4OPRM1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045966-B | Substituted heterocyclic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-106045967-B | Substituted heterocyclic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-106045966-A | Substituted heterocyclic compounds and application of same to medicines | 广东东阳光药业有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106045967-A | Substituted heterocyclic compounds and application of same to medicines | 广东东阳光药业有限公司 | 2016-10-26 | — | — | CN | disclosed |