Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linuron SCHEMBL27841525 | 0.91 | KMT2A (0.65) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL56566 | 0.90 | KMT2A (0.76) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL8406948 | 0.90 | KMT2A (0.76) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL27260336 | 0.90 | KMT2A (0.76) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL28168150 | 0.88 | KMT2A (0.72) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL9057322 | 0.86 | APEX1 (0.79) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL8476834 | 0.86 | KMT2A (0.60) | MEN1KMT2AAPEX1RAB9APKM | |
| Chloroxuron SCHEMBL8602342 | 0.85 | PKM (0.67) | MEN1KMT2AAPEX1RAB9APKM | |
| Linuron SCHEMBL8780339 | 0.85 | PKM (0.80) | MEN1KMT2AAPEX1RAB9APKM | |
| SCHEMBL11517285 | 0.84 | HPGD (0.66) | MEN1KMT2ARAB9APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873925-B | Antiparasitic and insecticidal isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-105873925-A | Antiparasitic and insecticidal isoxazoline compounds | 梅里亚股份有限公司 | 2016-08-17 | — | — | CN | disclosed |