Biphenyl

Biphenyl

SCHEMBL28097686

CC1=CC(=O)C=CC1=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.59
MAOA P21397 5/20 0.57
MAOB P27338 5/20 0.57
MAPT P10636 6/20 0.42
MAPK1 P28482 5/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
PKM P14618 3/20 0.42
LMNA P02545 3/20 0.42
THRB P10828 2/20 0.42
TP53 P04637 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTT P42858 2/20 0.42
S1PR2 O95136 1/20 0.42
XBP1 P17861 1/20 0.42
ALOX12 P18054 1/20 0.42
MPI P34949 1/20 0.42
RECQL P46063 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cresoquinone SCHEMBL49207 0.83
Cresoquinone SCHEMBL28348842 0.81 ERBB2 (0.44) HSD17B3MAOAMAOBMAPTMAPK1
Cresoquinone SCHEMBL28020551 0.81 MAOA (0.47) HSD17B3MAOAMAOBMAPTMAPK1
Cresoquinone SCHEMBL28970007 0.81 ERBB2 (0.44) HSD17B3MAOAMAOBMAPTMAPK1
Cresoquinone SCHEMBL27750381 0.81 ERBB2 (0.44) HSD17B3MAOAMAOBMAPTMAPK1
Biphenyl SCHEMBL321778 0.75 ALDH1A1 (0.60) HSD17B3MAOAMAOBMAPTMAPK1
Cresoquinone SCHEMBL9790691 0.75 ALDH1A1 (0.50) MAPTALDH1A1LMNATDP1MEN1
Ethane SCHEMBL28553030 0.74 MAOA (0.91) HSD17B3MAOAMAOBMAPTMAPK1
SCHEMBL10959950 0.74 HSD17B3 (1.00) HSD17B3MAOAMAOBMAPTMAPK1
Tannin Pyrogallol SCHEMBL28418431 0.73 HSD17B3 (0.62) HSD17B3MAOAMAOBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108940-A Flame retardant poly (arylene ether)/polystyrene foam and related methods of manufacture and articles 沙特基础工业全球技术有限公司 2017-08-29 CN disclosed
CN-105940044-A Fiber composite material 沙特基础工业全球技术有限公司 2016-09-14 CN disclosed
CN-104350189-B Poly (phenylene ether) fibers and methods of manufacture 沙特基础全球技术有限公司 2016-09-14 CN disclosed