Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | USP19 | O94966 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265475 | 0.79 | GAA (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1IKBKB | |
| SCHEMBL4852553 | 0.78 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL2364162 | 0.75 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL2903900 | 0.73 | USP1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL27996878 | 0.73 | GAA (0.55) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL5212183 | 0.72 | FAAH (0.48) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL7738122 | 0.72 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL4029802 | 0.71 | TSHR (0.38) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5505905 | 0.69 | USP1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL5638728 | 0.69 | ESR2 (0.49) | NPC1RAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279132-B | 2, 4-imidazoline diketone heterocyclic derivative and preparation method and application thereof | 四川大学华西医院 | 2019-11-26 | — | — | CN | disclosed |
| CN-106279132-A | 2, 4-imidazoline diketone heterocyclic derivative and preparation method and application thereof | 四川大学华西医院 | 2017-01-04 | — | — | CN | disclosed |