Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594842 | 0.84 | ELANE (0.56) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9576707 | 0.82 | SMN1; SMN2 (0.47) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL14625736 | 0.81 | PRSS1 (0.47) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL2729152 | 0.81 | PRSS1 (0.55) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL28073639 | 0.79 | CA1 (0.53) | PRSS1ACRSMN1; SMN2RAB9ACA12 | |
| SCHEMBL9577312 | 0.79 | SMN1; SMN2 (0.51) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11555462 | 0.79 | KMT2A (0.48) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL236821 | 0.77 | SMN1; SMN2 (0.56) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL28833766 | 0.75 | MAPT (0.51) | PRSS1ACRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL26814928 | 0.75 | SMN1; SMN2 (0.47) | PRSS1ACRSMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917094-B | Glucosylceramide Synthase Inhibitors | 建新公司 | 2016-11-09 | — | — | CN | disclosed |