SCHEMBL2729152

SCHEMBL2729152

CC(C)c1ccc(OC(N)=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.55
ACR P10323 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
HPGD P15428 1/20 0.50
XBP1 P17861 1/20 0.50
MAPT P10636 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
RAB9A P51151 2/20 0.47
KIF11 P52732 2/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
ADAMTS4 O75173 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL2733405 0.89 PRSS1 (0.48) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL236821 0.83 SMN1; SMN2 (0.56) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL6284986 0.82 KMT2A (0.64) PRSS1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL28097833 0.81 PRSS1 (0.50) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL1714626 0.81 LMNA (0.59) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL5699582 0.81 SMN1; SMN2 (0.54) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL5933001 0.81 SMN1; SMN2 (0.54) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL20472709 0.80 SMN1; SMN2 (0.50) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL28280156 0.80 KMT2A (0.44) PRSS1ACRSMN1; SMN2HPGDXBP1
SCHEMBL9360100 0.80 PRSS1 (0.49) PRSS1ACRSMN1; SMN2HPGDXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580596-A MIXTURE OF RAPE OIL METHYLESTER AND MEDIUM AND LONG-CHAIN ALCOHOLS CPC INTERNATIONAL INC. (US) 1996-12-03 US claimed
EP-4447683-B1 USE OF ISOXAZOLINECARBOXAMIDE FOR SPROUT INHIBITION BAYER AG (DE) 2025-08-13 EP disclosed
US-20250057164-A1 USE OF ISOXAZOLINECARBOXAMIDE FOR SPROUT INHIBITION BAYER AG (DE) 2025-02-20 US disclosed
WO-2023110813-A1 USE OF ISOXAZOLINECARBOXAMIDE FOR SPROUT INHIBITION BAYER AKTIENGESELLSCHAFT (DE) 2023-06-22 WO disclosed
WO-2019237919-A1 POLYNUCLEOTIDE AND METHOD FOR CONTROLLING INSECT INFESTATION 北京大北农生物技术有限公司 2019-12-19 WO disclosed
WO-2019237918-A1 POLYNUCLEOTIDE AND METHOD USED FOR CONTROLLING INSECT INVASION 北京大北农生物技术有限公司 2019-12-19 WO disclosed
WO-2019228151-A1 POLYNUCLEOTIDE AND METHOD FOR CONTROLLING INSECT INVASION 北京大北农生物技术有限公司 (CN) 2019-12-05 WO disclosed
EP-2755949-B1 FUNGICIDAL 4-SUBSTITUTED-3-{PHENYL[(HETEROCYCLYLMETHOXY)IMINO]METHYL}-1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER IP GMBH (DE) 2015-10-21 EP disclosed
US-9090600-B2 Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadizol-5(4H)-one derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-07-28 US disclosed
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-11-27 US disclosed
US-6710017-B2 Compositions and methods for controlling algae in recirculating water systems AVECIA, INC. 2004-03-23 US disclosed
EP-0653912-B1 SPROUT INHIBITOR FOR POTATOES PFANNI WERKE GMBH & CO KOMMAND (DE) 1999-10-06 EP disclosed
US-5580596-A MIXTURE OF RAPE OIL METHYLESTER AND MEDIUM AND LONG-CHAIN ALCOHOLS CPC INTERNATIONAL INC. (US) 1996-12-03 US disclosed
EP-0311632-B1 SURFACE ACTIVE LACTAMS ISP INVESTMENTS INC (US) 1996-05-29 EP disclosed
EP-0653912-A1 SPROUT INHIBITOR FOR POTATOES Pfanni Werke GmbH & Co. Kommanditgesellschaft (DE) 1995-05-24 EP disclosed
WO-1994028716-A2 SPROUT INHIBITOR FOR POTATOES PFANNI-WERKE GMBH & CO. KG (DE) 1994-12-22 WO disclosed
US-5294644-A Nonionic surfactants for solubility ISP INVESTMENTS INC. (US) 1994-03-15 US disclosed
EP-0311632-A4 SURFACE ACTIVE LACTAMS 1990-12-27 EP disclosed
EP-0311632-A1 SURFACE ACTIVE LACTAMS. GAF CORP (US) 1989-04-19 EP disclosed
WO-1988000184-A1 SURFACE ACTIVE LACTAMS GAF CORPORATION (US) 1988-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057164-A1 USE OF ISOXAZOLINECARBOXAMIDE FOR SPROUT INHIBITION API5, ING2, CDK5 PRSS1 4411/4885ACR 4768/4885SMN1; SMN2 3043/4885
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES CYP4X1, CYP4B1, CYP4Z1 PRSS1 3156/4885ACR 472/4885SMN1; SMN2 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.