Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | PPME1 | Q9Y570 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189646 | 0.72 | HTR6 (0.50) | RAPGEF4PPME1TSHR | |
| SCHEMBL14955691 | 0.71 | RAPGEF4 (0.40) | RAPGEF4TSHRSMN1; SMN2 | |
| SCHEMBL31738653 | 0.68 | KDM4E (0.41) | TSHR | |
| SCHEMBL30467032 | 0.62 | ALDH1A1 (0.31) | SMN1; SMN2 | |
| SCHEMBL5636978 | 0.61 | HTR6 (0.61) | RAPGEF4TSHR | |
| 1,2-Dichlorobenzene SCHEMBL28859926 | 0.59 | TSHR (0.62) | TSHRSMN1; SMN2 | |
| Chlorobenzene SCHEMBL7223075 | 0.59 | TSHR (0.69) | TSHRSMN1; SMN2 | |
| 1,4-Dichlorobenzene SCHEMBL28859925 | 0.57 | ALDH1A1 (0.58) | TSHR | |
| 1,4-Dichlorobenzene SCHEMBL2727174 | 0.57 | ALDH1A1 (0.58) | TSHR | |
| 1,2-Dichlorobenzene SCHEMBL10452828 | 0.57 | TSHR (0.59) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936716-B | Tool muscarinic receptor antagonists and the diamide compound of beta 2 adrenoreceptor agonists activity | 施万呼吸有限责任公司 | 2016-09-07 | — | — | CN | disclosed |