Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259674 | 0.88 | ACHE (0.59) | DHODHKDM4ESMN1; SMN2LMNAHPGD | |
| SCHEMBL16098232 | 0.88 | MAPK1 (0.54) | DHODHKDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL16099161 | 0.85 | ACACA (0.62) | MAPTKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL28634603 | 0.84 | DHODH (0.54) | DHODHMAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL20414562 | 0.84 | DHODH (0.49) | DHODHKDM4ESMN1; SMN2LMNAHPGD | |
| SCHEMBL28231738 | 0.84 | CYP19A1 (0.58) | DHODHKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL29399396 | 0.83 | ACACA (0.65) | DHODHMAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL19050396 | 0.83 | ACACA (0.65) | DHODHMAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL8956179 | 0.83 | ACACA (0.65) | DHODHMAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10610835 | 0.82 | SMN1; SMN2 (0.51) | DHODHMAPTKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873588-A | Compounds for the treatment of cancer and uses thereof | 戈里奥诺瓦公司 | 2016-08-17 | — | — | CN | disclosed |