Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | ACP1 | P24666 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619856 | 0.85 | ACHE (0.56) | DHODHL3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL28622146 | 0.85 | ALDH1A1 (0.50) | DHODHACP1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL28098502 | 0.84 | DHODH (0.53) | DHODHACP1MAPTMAPK1NPC1 | |
| SCHEMBL28622149 | 0.84 | MAPK1 (0.56) | DHODHMAPTMAPK1NPC1RAB9A | |
| SCHEMBL13848609 | 0.82 | DHODH (0.52) | DHODHACP1MAPTL3MBTL1NPC1 | |
| SCHEMBL16099161 | 0.79 | ACACA (0.62) | ACP1MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL6534331 | 0.79 | NPC1 (0.54) | DHODHACP1MAPTL3MBTL1MAPK1 | |
| SCHEMBL27791832 | 0.78 | MAPT (0.47) | MAPTL3MBTL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL29399396 | 0.78 | ACACA (0.65) | DHODHACP1MAPTL3MBTL1MAPK1 | |
| SCHEMBL19050396 | 0.78 | ACACA (0.65) | DHODHACP1MAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277978-B | Preparation method of 2, 4-disubstituted quinoline compound | 河南师范大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113277978-A | Preparation method of 2, 4-disubstituted quinoline compound | 河南师范大学 | 2021-08-20 | — | — | CN | disclosed |