Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20599691 | 0.98 | KDM4E (0.36) | KDM4EASPHKDM8 | |
| SCHEMBL2696087 | 0.79 | KDM4E (0.46) | KDM4EASPHKDM8 | |
| SCHEMBL13886916 | 0.75 | MAPT (0.38) | KDM4E | |
| SCHEMBL30931204 | 0.75 | MAPT (0.38) | KDM4E | |
| Hydrochloric Acid SCHEMBL3142889 | 0.73 | MAPT (0.37) | KDM4E | |
| Formic Acid SCHEMBL2588636 | 0.73 | KDM4E (0.41) | KDM4EASPHKDM8 | |
| SCHEMBL15555561 | 0.72 | KDM4E (0.47) | KDM4EASPHKDM8 | |
| SCHEMBL644769 | 0.72 | KDM4E (0.68) | KDM4EASPHKDM8 | |
| SCHEMBL28401793 | 0.70 | — | — | |
| SCHEMBL28410376 | 0.68 | LMNA (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302626-B | 4, 4-disubstituted-1, 4-dihydropyrimidines and their use as medicaments for the treatment of hepatitis b | 爱尔兰詹森科学公司 | 2016-09-07 | — | — | CN | disclosed |