Demannose

Demannose

SCHEMBL28098542

COC(=O)C(C)O.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.46

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 2/20 0.36
PDE4A P27815 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
PAX8 Q06710 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL3935915 0.85 LMNA (0.35) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL18451400 0.84 LMNA (0.41) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL26132949 0.84 PDE4A (0.44) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL127458 0.84 LMNA (0.48) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL23929879 0.82 LMNA (0.42) LMNAL3MBTL1KDM4EPDE4ATDP1
Galactose SCHEMBL9726398 0.82 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
Galactose SCHEMBL10596615 0.82 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL5471738 0.82 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL23929878 0.82 LMNA (0.42) LMNAL3MBTL1KDM4EPDE4ATDP1
Demannose SCHEMBL30410784 0.82 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105949053-B The method that support type nickel oxide catalysis monosaccharide conversion prepares methyl lactate in near-critical methanol medium 浙江大学 2019-05-07 CN disclosed
CN-108772100-A A kind of heteropolyacid salt solid catalyst and its preparation method and application 广东工业大学 2018-11-09 CN disclosed
CN-105949053-A Method for preparing methyl lactate through supported nickel oxide catalyzed monosaccharide conversion in near critical methanol medium 浙江大学 2016-09-21 CN disclosed