Demannose

Demannose

SCHEMBL3935915

CCOC(=O)C(C)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL11509807 0.85 LMNA (0.47) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL28098542 0.85 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL5541835 0.85 LMNA (0.47) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL20701787 0.84 ALOX15 (0.48) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL20701790 0.84 ALOX15 (0.48) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL15066411 0.83 GLO1 (0.40) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL3516865 0.81 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL3935927 0.81 PDE4A (0.47) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL15085556 0.81 TSHR (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL23929878 0.81 LMNA (0.42) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041264-A2 PRODUCTION OF D-LACTIC ACID WITH YEAST Tate & Lyle Ingredients Americas, Inc. (US) 2009-04-01 EP disclosed
WO-2007149894-A2 PRODUCTION OF D-LACTIC ACID WITH YEAST TATE & LYLE INGREDIENTS AMERICAS, INC. (US) 2007-12-27 WO disclosed