Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15441571 | 0.85 | YAP1 (0.52) | GSK3BBACE1PTPN1NR1H4HPGD | |
| SCHEMBL13280881 | 0.80 | PRMT5 (0.49) | GSK3BBACE1PTPN1HPGDPOLB | |
| SCHEMBL13278903 | 0.77 | PTPN1 (0.56) | GSK3BBACE1PTPN1NR1H4HPGD | |
| SCHEMBL10547399 | 0.77 | MAOB (0.52) | GSK3BBACE1PTPN1NR1H4HPGD | |
| SCHEMBL14720576 | 0.76 | SRD5A1 (0.52) | HPGDHDAC2SRD5A1 | |
| SCHEMBL14722165 | 0.75 | SRD5A1 (0.51) | HDAC2SRD5A1 | |
| SCHEMBL14720706 | 0.75 | SRD5A1 (0.51) | HDAC2SRD5A1 | |
| SCHEMBL16874748 | 0.74 | PRMT5 (0.56) | HPGDMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL22683282 | 0.74 | SRD5A1 (0.50) | HDAC2SRD5A1 | |
| SCHEMBL12813411 | 0.74 | TP53 (0.51) | POLBNR4A1NR4A2NR4A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596960-B | 6, 7-dihydroimidazo [2,1-B ] [1,3] oxazine fungicides | 大塚制药株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-103596960-A | 6, 7-dihydroimidazo [2,1-B ] [1,3] oxazine fungicides | OTSUKA PHARMA CO LTD | 2014-02-19 | — | — | CN | disclosed |