Pyridine

Pyridine

SCHEMBL28098609

Cc1ccn(C)n1.c1ccncc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.38
NAPRT Q6XQN6 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KEAP1 Q14145 1/20 0.34
NOS1 P29475 1/20 0.34
JMJD6 Q6NYC1 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
EPHX2 P34913 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75314 0.84
Hydrochloric Acid SCHEMBL27901405 0.82
Pyridine SCHEMBL27957296 0.78 KMT2A (0.44) KMT2AMAPTSMN1; SMN2TSHRNAPRT
Formamide SCHEMBL10967419 0.77 KEAP1 (0.39) KMT2ARAB9ANPC1MAPTATM
SCHEMBL2551980 0.76 KMT2A (0.40) KMT2ARAB9ANPC1MAPTATM
SCHEMBL27487661 0.75 KMT2A (0.45) KMT2ARAB9ANPC1MAPTATM
Oxazole SCHEMBL27523520 0.73 KMT2A (0.32) KMT2ARAB9ANPC1MAPTATM
Piperazine SCHEMBL28075211 0.72 KMT2A (0.38) KMT2ARAB9ANPC1MAPTATM
Phosphoric Acid SCHEMBL7647885 0.72 RAB9A (0.42) KMT2ARAB9ANPC1MAPTATM
Succinic Acid SCHEMBL22123041 0.72 KDM4E (0.45) KMT2ARAB9ANPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721481-A A method of carbon dioxide being added in oxidizing atmosphere and improves effective selectivity of product 中国石油化工股份有限公司 2019-05-07 CN disclosed
CN-108602913-A The method for preparing highly reactive isobutylene homo or copolymer 巴斯夫欧洲公司 2018-09-28 CN disclosed
CN-108602914-A Method for producing highly reactive isobutene homo-or copolymers 巴斯夫欧洲公司 2018-09-28 CN disclosed
CN-104583273-B Polyimide precursor, polyimides, polyimide film, polyimide metal laminate and polyimide solution 国立大学法人岩手大学 2018-01-30 CN disclosed
CN-103676522-B Cleaning balde, handle box and image processing system 富士施乐株式会社 2017-08-18 CN disclosed
CN-104245844-B The manufacture method of electric conductivity polyimide film 株式会社钟化 2016-12-21 CN disclosed
CN-105936823-A Composite for etching treatment and etching treatment method 大金工业株式会社 2016-09-14 CN disclosed