Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098678 | 0.86 | GAA (0.46) | GAARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL16797142 | 0.79 | ALDH1A1 (0.51) | GAARAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL27840194 | 0.73 | ALDH1A1 (0.41) | GAARAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3160005 | 0.71 | GAA (0.72) | GAARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL27739015 | 0.71 | ALDH1A1 (0.46) | GAARAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL16797151 | 0.70 | ALDH1A1 (0.58) | GAARAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL30539447 | 0.70 | ALDH1A1 (0.55) | GAARAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL11487222 | 0.69 | MAPT (0.54) | GAARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL27792549 | 0.68 | CA12 (0.41) | ALDH1A1POLBMAPK1TDP1KDM4E | |
| SCHEMBL3158438 | 0.68 | GAA (0.61) | GAARAB9ANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980364-A | Bicyclic heteroaryl indole analogs useful as ROR γ modulators | 格兰马克药品股份有限公司 | 2016-09-28 | — | — | CN | disclosed |