Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098672 | 0.86 | GAA (0.43) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL16797138 | 0.82 | GAA (0.46) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL16797142 | 0.70 | ALDH1A1 (0.51) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4246567 | 0.69 | ALDH1A1 (0.61) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27840194 | 0.68 | ALDH1A1 (0.41) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2062047 | 0.67 | L3MBTL1 (0.43) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27739015 | 0.66 | ALDH1A1 (0.46) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27792549 | 0.66 | CA12 (0.41) | ALDH1A1LMNAKDM4EPOLBTDP1 | |
| SCHEMBL4238253 | 0.65 | L3MBTL1 (0.49) | GAANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27959687 | 0.65 | ALDH1A1 (0.41) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980364-A | Bicyclic heteroaryl indole analogs useful as ROR γ modulators | 格兰马克药品股份有限公司 | 2016-09-28 | — | — | CN | disclosed |