Ajoene

Ajoene

SCHEMBL28098809

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nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.39
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ajoene SCHEMBL17873665 1.00 PTGS2 (0.39) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Ajoene SCHEMBL1843901 0.90 PTGS2 (0.46) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Ajoene SCHEMBL3341700 0.90 PTGS2 (0.46) PTGS2TRPA1ALDH1A1CYP3A4HPGD
(Z)-Ajoene SCHEMBL3305767 0.90 PTGS2 (0.46) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Ajoene SCHEMBL3341704 0.90 PTGS2 (0.46) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Ajoene SCHEMBL465526 0.90 PTGS2 (0.46) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Allicin SCHEMBL27662099 0.84 PTGS2 (0.39) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Ajoene SCHEMBL17785554 0.81 PTGS2 (0.42) PTGS2TRPA1ALDH1A1CYP3A4HPGD
Allicin SCHEMBL1492144 0.79 TRPA1 (0.50) TRPA1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL10728708 0.78 PTGS2 (0.34) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105919135-A Garlic extract composite preparation and its preparation method and use 上海春芝堂生物制品有限公司 2016-09-07 CN disclosed