Dl-Tryptophan

Dl-Tryptophan

SCHEMBL28099063

CCCNC(CCO)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.65
▸ KDM4E B2RXH2 3/20 0.65
▸ MAPT P10636 3/20 0.65
▸ MEN1 O00255 2/20 0.65
▸ LMNA P02545 2/20 0.65
▸ TSHR P16473 2/20 0.65
▸ BLM P54132 2/20 0.65
▸ PMP22 Q01453 2/20 0.65
▸ MPO P05164 1/20 0.65
▸ HIF1A Q16665 1/20 0.65
▸ ALOX15 P16050 2/20 0.51
▸ ACE P12821 3/20 0.50
▸ APAF1 O14727 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ ERAP2 Q6P179 2/20 0.49
▸ ERAP1 Q9NZ08 2/20 0.49
▸ LNPEP Q9UIQ6 2/20 0.49
▸ ITGB2 P05107 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL28196606 0.87 MEN1 (0.49) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL3851355 0.85 MEN1 (0.66) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL27562072 0.83 KDM4E (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL30045975 0.83 KDM4E (0.89) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL3423849 0.82 KDM4E (0.82) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL27962058 0.82 KDM4E (0.97) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL27962055 0.82 KDM4E (0.97) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL5065251 0.81 KDM4E (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL27798727 0.81 KDM4E (0.89) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL5065247 0.81 KDM4E (0.89) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110064077-A A kind of uterine cavity is adhered the silk fibroin hydrogel for the treatment of 温州医科大学 2019-07-30 — — CN disclosed
CN-106065381-B Composition and method comprising serine protease variants 宝洁公司 2019-07-26 — — CN disclosed
CN-110038166-A A kind of film of curling certainly and preparation method thereof applied to neural restoration 温州医科大学 2019-07-23 — — CN disclosed
CN-108267580-A A kind of active group using specific dipeptides inhibits the immunoturbidimetry reagent of IgM types RF interference 南京天纵易康生物科技股份有限公司 2018-07-10 — — CN disclosed
CN-107106607-A Triple transgenic pig suitable for xenotransplantation 印第安纳大学研究与技术公司 2017-08-29 — — CN disclosed
CN-107002062-A Terpene synthases from the franticosa variant (Cananga odorata var. fructicosa) of Cananga 淡马锡生命科学研究院有限公司 2017-08-01 — — CN disclosed
CN-102858970-B Composition and method comprising misfolded proteins enzyme 丹尼斯科美国公司 2017-07-21 — — CN disclosed
CN-103502446-B compositions and methods comprising serine protease variants THE PROCTER & GAMBLE CO. (US) 2016-11-30 — — CN disclosed
CN-106065381-A Comprise compositions and the method for serine protease variants 宝洁公司 2016-11-02 — — CN disclosed
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