Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626188 | 0.68 | ACHE (0.33) | MAPTALDH1A1LMNAPOLB | |
| SCHEMBL9909113 | 0.64 | — | — | |
| Formaldehyde SCHEMBL27956974 | 0.64 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLB | |
| SCHEMBL19062252 | 0.63 | ALDH1A1 (0.31) | ALDH1A1POLB | |
| SCHEMBL27949322 | 0.63 | — | — | |
| SCHEMBL14392214 | 0.55 | LMNA (0.33) | MAPTALDH1A1LMNA | |
| SCHEMBL8602719 | 0.54 | — | — | |
| SCHEMBL9719333 | 0.54 | — | — | |
| SCHEMBL16173997 | 0.53 | — | — | |
| SCHEMBL9921594 | 0.53 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820236-A | Histone acetyltransferase small molecule inhibitor and preparation method and application thereof | 复旦大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-105873919-A | Substituted uracils as chymase inhibitors | 拜耳医药股份有限公司 | 2016-08-17 | — | — | CN | disclosed |