Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713124 | 0.78 | NFE2L2 (0.56) | NFE2L2TRPA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23457275 | 0.78 | NFE2L2 (0.56) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4579398 | 0.77 | NFE2L2 (0.62) | NFE2L2TRPA1 | |
| SCHEMBL9488120 | 0.77 | NFE2L2 (0.62) | NFE2L2TRPA1 | |
| SCHEMBL1759710 | 0.76 | NFE2L2 (0.54) | NFE2L2TRPA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4128400 | 0.73 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4890473 | 0.73 | NFE2L2 (0.50) | NFE2L2TRPA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8112257 | 0.73 | NFE2L2 (0.50) | NFE2L2LMNA | |
| SCHEMBL10369921 | 0.73 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15353049 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |