Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2130736 | 0.95 | — | — | |
| Ethylene SCHEMBL3296366 | 0.87 | — | — | |
| Acetic Acid SCHEMBL27129104 | 0.86 | FFAR3 (0.33) | — | |
| Carbamic Acid SCHEMBL27869277 | 0.86 | ACHE (0.33) | — | |
| SCHEMBL14938709 | 0.86 | — | — | |
| Ethylene SCHEMBL9807203 | 0.85 | — | — | |
| Acrylic Acid SCHEMBL381788 | 0.85 | LMNA (0.42) | — | |
| Acetic Acid SCHEMBL10883458 | 0.84 | FFAR3 (0.32) | — | |
| Urea SCHEMBL886861 | 0.83 | ALDH1A1 (0.30) | — | |
| Methacrylic Acid SCHEMBL733608 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105917270-A | Contact lens with a hydrophilic layer | 视觉力学有限责任公司 | 2016-08-31 | — | — | CN | disclosed |