Benzene

Benzene

SCHEMBL28099609

O=C1NC(=O)c2c(F)cccc21.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
PARP1 P09874 6/20 0.47
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CASP3 P42574 5/20 0.43
CASP7 P55210 2/20 0.43
CASP2 P42575 1/20 0.43
CASP6 P55212 1/20 0.43
CASP8 Q14790 1/20 0.43
AKR1A1 P14550 1/20 0.42
AKR1B1 P15121 1/20 0.42
TTR P02766 1/20 0.41
GRM5 P41594 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29578942 0.98 GSK3B (0.52) GSK3BCA1CA2CA7CA9
SCHEMBL1080129 0.98 GSK3B (0.52) GSK3BCA1CA2CA7CA9
SCHEMBL8273030 0.80 CA1 (0.46) GSK3BCA1CA2CA7CA9
SCHEMBL16754925 0.80 GSK3B (0.62) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL1081008 0.79 GSK3B (0.43) GSK3BCA1CA2CA7CA9
SCHEMBL32089673 0.79 GSK3B (0.43) GSK3BCA1CA2CA7CA9
SCHEMBL9279943 0.78 CA1 (0.39) GSK3BCA1CA2CA7CA9
SCHEMBL29089233 0.77 PARP1 (0.66) GSK3BCA1CA2CA7CA9
SCHEMBL135332 0.75 GSK3B (0.56) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL30956736 0.75 CASP3 (0.48) GSK3BPARP1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104311825-B Phenolphthalein type copolyimide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2017-05-17 CN disclosed
CN-105985521-A Polybenzimidazole imide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2016-10-05 CN disclosed