SCHEMBL28099996

SCHEMBL28099996

CC(C)(C)CC(C)(C)c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.44
CYP3A4 P08684 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TAAR1 Q96RJ0 1/20 0.38
ALDH1A1 P00352 3/20 0.36
KIF11 P52732 2/20 0.35
RXRA P19793 4/20 0.35
RXRB P28702 4/20 0.35
PTPN1 P18031 2/20 0.35
RXRG P48443 2/20 0.35
CYP2D6 P10635 3/20 0.35
HIF1A Q16665 2/20 0.35
LOXL2 Q9Y4K0 2/20 0.35
LMNA P02545 2/20 0.34
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 2/20 0.34
APAF1 O14727 2/20 0.34
USP2 O75604 2/20 0.34
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29538635 0.86 KIF11 (0.46) SHBGCYP3A4SMN1; SMN2TAAR1KIF11
SCHEMBL42933 0.78 SHBG (0.60) SHBGCYP3A4SMN1; SMN2TAAR1ALDH1A1
SCHEMBL199858 0.78 SMN1; SMN2 (0.39) SHBGCYP3A4SMN1; SMN2TAAR1ALDH1A1
SCHEMBL199860 0.78 SHBG (0.47) SHBGCYP3A4SMN1; SMN2ALDH1A1PTPN1
SCHEMBL17772188 0.77 CYP3A4 (0.39) SHBGCYP3A4SMN1; SMN2KIF11
SCHEMBL5546207 0.76 RXRB (0.53) ALDH1A1KIF11RXRARXRBRXRG
SCHEMBL26149393 0.76 RXRB (0.53) ALDH1A1KIF11RXRARXRBRXRG
Water SCHEMBL28217447 0.76 SHBG (0.58) SHBGCYP3A4SMN1; SMN2TAAR1ALDH1A1
SCHEMBL29704027 0.74 CYP3A4 (0.36) SHBGCYP3A4SMN1; SMN2TAAR1HIF1A
SCHEMBL30096028 0.74 RXRB (0.57) ALDH1A1KIF11RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619987-B Color converter 巴斯夫欧洲公司 2016-11-16 CN disclosed