Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480841 | 0.80 | TERT (0.38) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL5847804 | 0.77 | CES2 (0.42) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL28218126 | 0.72 | CES2 (0.38) | CES2CES1MEN1KMT2ACA1 | |
| SCHEMBL27541249 | 0.70 | CES2 (0.44) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL7165481 | 0.69 | MAPT (0.43) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL15694511 | 0.69 | CES2 (0.42) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL13554366 | 0.68 | HTR7 (0.44) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL28338821 | 0.67 | CES2 (0.41) | TERTCES2CES1MEN1KMT2A | |
| SCHEMBL6683261 | 0.66 | HPGD (0.46) | CES2CES1MEN1KMT2ACYP1A2 | |
| SCHEMBL10452374 | 0.65 | MAPT (0.46) | TERTCES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619698-B | Pyrrolidin derivatives and the purposes as complement pathway regulator thereof | 诺华股份有限公司 | 2016-08-31 | — | — | CN | disclosed |