Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72379 | 0.92 | KDM4E (0.70) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL5396165 | 0.88 | KDM4E (0.68) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL28046848 | 0.85 | KDM4E (0.55) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL69125 | 0.83 | KDM4E (0.64) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL29450085 | 0.83 | KDM4E (0.64) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL28568288 | 0.83 | KDM4E (0.52) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL2467305 | 0.83 | ALDH1A1 (0.65) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL31389316 | 0.83 | KDM4E (0.54) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL561686 | 0.83 | KDM4E (0.54) | KDM4EMEN1KMT2AALOX15LMNA | |
| SCHEMBL6605024 | 0.82 | KDM4E (0.65) | KDM4EMEN1KMT2ALMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106687455-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106380446-A | Synthesis method of quinoline-2-formic acid ester derivatives | 南阳师范学院 | 2017-02-08 | — | — | CN | disclosed |
| CN-106366035-A | Method for synthesizing quinoline derivative | 南阳师范学院 | 2017-02-01 | — | — | CN | disclosed |
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |