SCHEMBL69125

SCHEMBL69125

O=C(O)c1cc(C(=O)O)c2ccccc2n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
LMNA P02545 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
PDE10A Q9Y233 1/20 0.64
DHODH Q02127 2/20 0.60
ALOX15 P16050 1/20 0.60
POLB P06746 3/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
AKR1C3 P42330 1/20 0.54
AKR1C2 P52895 1/20 0.54
AKR1C1 Q04828 1/20 0.54
ALDH1A1 P00352 1/20 0.54
ESR1 P03372 1/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
GAA P10253 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450085 1.00 KDM4E (0.64) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL16832253 0.87 KDM4E (0.58) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL13209726 0.87 ALOX15 (0.59) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL5396165 0.83 KDM4E (0.68) KDM4ELMNADHODHALOX15POLB
SCHEMBL16832508 0.83 KDM4E (0.54) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL28100588 0.83 KDM4E (0.60) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL28046850 0.83 ALOX15 (0.55) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL16832577 0.83 KDM4E (0.54) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL18746 0.82 KDM4E (0.83) KDM4ELMNASMN1; SMN2PDE10ADHODH
SCHEMBL29359819 0.82 KDM4E (0.83) KDM4ELMNASMN1; SMN2PDE10ADHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO claimed
US-20250325567-A1 COADMINISTRATION OF POLYCANNABINOID WITH AMINE/AMIDE ANESTHETICS TO ENHANCE EFFICACY AGAINST PAIN UNIV CONNECTICUT (US) 2025-10-23 US claimed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
US-20250122395-A1 POLYCANNABINOIDS FOR COMMODITY POLYMERS AND COMMODITY ELECTRONICS PURDUE RESEARCH FOUNDATION 2025-04-17 US claimed
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
WO-2024232872-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2024-11-14 WO claimed
CN-102924374-B Preparation method for quinoline-4-carboxylic acid derivative HUBEI SHINREZING PHARMACEUTICAL CO LTD 2014-04-16 CN claimed
US-8460534-B2 Chromium(VI)-free black passivation of surfaces containing zinc ATOTECH DEUTSCHLAND GMBH (DE) 2013-06-11 US claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
CN-101668882-B Chromium(vi)-free black passivation of surfaces containing zinc ATOTECH DEUTSCHLAND GMBH 2012-07-25 CN claimed
EP-1970470-B1 Chrome(VI)-free black passivates for surfaces containing zinc ATOTECH DEUTSCHLAND GMBH (DE) 2011-05-11 EP claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-20100133113-A1 CHROMIUM(VI)-FREE BLACK PASSIVATION OF SURFACES CONTAINING ZINC ATOTECH DEUTSCHLAND GMBH (DE) 2010-06-03 US claimed
EP-0565753-A1 Improved hair-shampoo-conditioner composition HELENE CURTIS, INC. (US) 1993-10-20 EP claimed
US-5137715-A Anionic surfactant, uncrosslinked polyamide, carrier and water HELENE CURTIS, INC. (US) 1992-08-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325567-A1 COADMINISTRATION OF POLYCANNABINOID WITH AMINE/AMIDE ANESTHETICS TO ENHANCE EFFICACY AGAINST PAIN CNR2, CNR1, OPRL1 KDM4E 2582/4885LMNA 3092/4885SMN1; SMN2 1340/4885
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE KDM4E 421/4885LMNA 2914/4885SMN1; SMN2 1633/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 KDM4E 2504/4885LMNA 1561/4885SMN1; SMN2 4595/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA KDM4E 1109/4885LMNA 833/4885SMN1; SMN2 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.