Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.49 |
| ▸ | CA9 | Q16790 | 9/20 | 0.49 |
| ▸ | CA1 | P00915 | 9/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL28725781 | 0.83 | CA2 (0.57) | LMNAALDH1A1CYP3A4HTR6CA2 | |
| Sulfanilamide SCHEMBL27481871 | 0.80 | CA2 (0.57) | LMNAALDH1A1CYP3A4HTR6CA2 | |
| Sulfanilamide SCHEMBL28086729 | 0.78 | CA2 (0.50) | LMNAALDH1A1CYP3A4HTR6CA2 | |
| SCHEMBL12015 | 0.78 | CCR1 (0.41) | LMNATDP1 | |
| SCHEMBL29520064 | 0.78 | CCR1 (0.41) | LMNATDP1 | |
| SCHEMBL27990718 | 0.76 | CCR1 (0.40) | LMNATDP1 | |
| Sulfanilamide SCHEMBL9832120 | 0.75 | CA2 (0.50) | LMNACA2CA9CA1CA12 | |
| SCHEMBL282262 | 0.74 | MEN1 (0.58) | ALDH1A1CYP3A4TSHRTDP1SMN1; SMN2 | |
| Sulfadimethoxine SCHEMBL9486265 | 0.74 | ALDH1A1 (0.90) | LMNAALDH1A1CYP3A4HTR6CYP2C19 | |
| Sulfanilamide SCHEMBL8197658 | 0.74 | CA2 (0.81) | LMNAALDH1A1CYP3A4HTR6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106124659-A | The method of prediction sulfa antibiotics rate of photocatalytic oxidation | 井冈山大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106543049-A | The preparation method of sulfonamides hapten and its conjugated antigen and application | 中国农业大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-106540668-A | Magnetic hydrophilic molecules trace composite and preparation method thereof | 中华人民共和国淮安出入境检验检疫局 | 2017-03-29 | — | — | CN | disclosed |
| CN-106536518-A | Anthelmintic compounds | 梅里亚股份有限公司 | 2017-03-22 | — | — | CN | disclosed |