Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331387 | 1.00 | FOLH1 (0.47) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL43996 | 0.81 | FOLH1 (0.66) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL9875634 | 0.81 | FOLH1 (0.66) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL43995 | 0.81 | FOLH1 (0.66) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL27858773 | 0.78 | ALDH1A1 (0.45) | CA1CA2 | |
| Pyrrole SCHEMBL28847693 | 0.77 | FOLH1 (0.54) | FOLH1CPB2CA1CA2SLC15A2 | |
| 2-Pyrrolidone SCHEMBL28915581 | 0.72 | CPB2 (0.46) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL24141430 | 0.71 | FOLH1 (0.54) | FOLH1CPB2CA1CA2SLC15A2 | |
| SCHEMBL12572609 | 0.70 | FOLH1 (0.83) | FOLH1CPB2SLC6A5GSR | |
| SCHEMBL1006178 | 0.69 | FOLH1 (0.64) | FOLH1CPB2CA1CA2SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234562-A | Means and methods for treating pathological aggregation | 非营利性组织佛兰芒综合大学生物技术研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-110494443-A | The sub- polypeptide of shiga toxin A Effect of subunit, shiga toxin effect submounts and cell-targeting molecule for locus specificity conjugation | MOLECULAR TEMPLATES INC | 2019-11-22 | — | — | CN | disclosed |
| CN-110087671-A | FGF21 compound/GLP-1R agonist combinations with optimized activity ratio | 赛诺菲 | 2019-08-02 | — | — | CN | disclosed |
| CN-104334576-B | Site-specific labeling methods and molecules produced thereby | 诺华股份有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-107266579-A | Fusion protein for treating metabolic disease | 诺华股份有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-103945871-B | Fusion proteins for the treatment of metabolic diseases | 诺华股份有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-106432510-A | Dual function proteins for treating metabolic disorders | 诺华股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104024273-B | Bifunctional proteins for the treatment of metabolic diseases | 诺华股份有限公司 | 2016-10-12 | — | — | CN | disclosed |