Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28279688 | 0.86 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28096701 | 0.84 | OPRM1 (0.33) | — | |
| Ethoxycarbonyl Group SCHEMBL27698635 | 0.83 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28100810 | 0.83 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL27837406 | 0.81 | — | — | |
| Cyclohexane SCHEMBL27780395 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| Cyclopentane SCHEMBL8158405 | 0.78 | ALDH1A1 (0.32) | — | |
| Cyclopentane SCHEMBL28273622 | 0.78 | ALDH1A1 (0.32) | — | |
| Cyclohexane SCHEMBL27851344 | 0.78 | ALDH1A1 (0.32) | — | |
| Ethoxycarbonyl Group SCHEMBL27739080 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916855-B | Substituted 4, 5, 6, 7-tetrahydropyrazolo [1,5-a ] pyrazine derivatives as casein kinase 1D/E inhibitors | 百时美施贵宝公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-107641105-A | N substituted imidazole carboxylic acid ester compounds and preparation method thereof and purposes in medicine | 四川海思科制药有限公司 | 2018-01-30 | — | — | CN | disclosed |
| CN-105916855-A | Substituted 4,5,6, 7-tetrahydropyrazolo [1,5-a ] pyrazine derivatives as casein kinase 1D/E inhibitors | 百时美施贵宝公司 | 2016-08-31 | — | — | CN | disclosed |