Urea

Urea

SCHEMBL28100950

C1=Cc2ccccc2ON1.NC(N)=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
SCN4A P35499 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
ATM Q13315 1/20 0.34
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
TRPA1 O75762 2/20 0.33
CYP2C9 P11712 1/20 0.32
GAA P10253 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
PARP1 P09874 1/20 0.30
CYP2C19 P33261 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL6652912 0.95 TSHR (0.34) TSHRLMNAMAPK1SCN4ASCN5A
Bicarbonate SCHEMBL28655831 0.91 MEN1 (0.33) MAPTKDM4EMEN1ALDH1A1KMT2A
Acetone SCHEMBL25211182 0.89 GAA (0.33) LMNAMAPTKDM4EMEN1ALDH1A1
SCHEMBL8924 0.88 MAPT (0.37) MAPTKDM4EMEN1ALDH1A1KMT2A
SCHEMBL29804885 0.88 MAPT (0.37) MAPTKDM4EMEN1ALDH1A1KMT2A
SCHEMBL3662203 0.88 MAPT (0.37) MAPTKDM4EMEN1ALDH1A1KMT2A
SCHEMBL16341187 0.88 MAPT (0.37) MAPTKDM4EMEN1ALDH1A1KMT2A
Propionic Acid SCHEMBL19423436 0.87 CES2 (0.32) TSHRLMNAMAPK1SCN4ASCN5A
Hypochlorous Acid SCHEMBL28601813 0.86 MAPT (0.33) MAPTKDM4EMEN1ALDH1A1KMT2A
Methylamine SCHEMBL6415767 0.86 MAPT (0.36) MAPTKDM4EMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105968350-A High-toughness polyether urea benzoxazine resin and preparation method thereof 合肥工业大学 2016-09-28 CN disclosed
CN-105968350-A High-toughness polyether urea benzoxazine resin and preparation method thereof 合肥工业大学 2016-09-28 CN disclosed