SCHEMBL28101059

SCHEMBL28101059

O=Cc1ccccc1OC(=O)Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
LMNA P02545 3/20 0.61
GAA P10253 1/20 0.61
PTGDR2 Q9Y5Y4 1/20 0.54
ALDH1A1 P00352 5/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SRC P12931 2/20 0.49
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
MEN1 O00255 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
TLR2 O60603 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006065 0.90 ALDH1A1 (0.59) KMT2ALMNAGAAPTGDR2ALDH1A1
SCHEMBL6238224 0.80 PTGDR2 (0.61) KMT2ALMNAGAAPTGDR2ALDH1A1
SCHEMBL29445574 0.80 PTGDR2 (0.61) KMT2ALMNAGAAPTGDR2ALDH1A1
SCHEMBL9241160 0.79 TDP1 (0.54) KMT2AALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL27352197 0.79 TDP1 (0.54) KMT2AALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL18073 0.79 TDP1 (0.54) KMT2AALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL9353455 0.79 TDP1 (0.54) KMT2AALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL9353461 0.79 TDP1 (0.54) KMT2AALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL1665178 0.79 HPGD (0.58) KMT2ALMNAGAAPTGDR2ALDH1A1
SCHEMBL10356911 0.79 MAPT (0.47) KMT2ALMNAGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106457782-A Laminated body with sealant film 沙特基础工业全球技术有限公司 2017-02-22 CN claimed
CN-106103590-B Polycarbonate compositions, their preparation method and its product 沙特基础工业全球技术有限公司 2017-10-24 CN disclosed
CN-106457782-A Laminated body with sealant film 沙特基础工业全球技术有限公司 2017-02-22 CN disclosed
CN-106103590-A Polycarbonate compositions, their preparation method and goods thereof 沙特基础工业全球技术有限公司 2016-11-09 CN disclosed