Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopyridine SCHEMBL28404259 | 0.84 | GPR119 (0.53) | GPR119MAPK1POLBCKS1BSKP1 | |
| 2-Picolinic Acid SCHEMBL28152526 | 0.82 | L3MBTL1 (0.43) | GPR119MAPK1L3MBTL1LMNANAPRT | |
| SCHEMBL28863731 | 0.82 | GPR119 (0.51) | GPR119MAPK1POLBCKS1BSKP1 | |
| 2-Pyridinecarboxaldehyde SCHEMBL6182995 | 0.82 | GPR119 (0.51) | GPR119MAPK1POLBCKS1BSKP1 | |
| Pyridine SCHEMBL28276860 | 0.82 | MAPK1 (0.49) | GPR119MAPK1POLBGRM5 | |
| Benzene SCHEMBL29155321 | 0.81 | USP2 (0.53) | GPR119MAPK1POLBCKS1BSKP1 | |
| SCHEMBL1088005 | 0.81 | L3MBTL1 (0.69) | GPR119L3MBTL1POLBCKS1BSKP1 | |
| SCHEMBL28241913 | 0.80 | MAPK1 (0.50) | GPR119MAPK1LMNAPOLBCKS1B | |
| SCHEMBL14122068 | 0.79 | GPR119 (0.55) | GPR119MAPK1L3MBTL1POLBCKS1B | |
| Methyl Alcohol SCHEMBL28769289 | 0.78 | USP2 (0.56) | GPR119MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103814024-B | Benzylpiperidine compound as lysophosphatidic acid (LPA) receptor antagonist | 默克专利股份公司 | 2016-11-23 | — | — | CN | disclosed |