Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813653 | 0.98 | GAA (0.30) | — | |
| Bromide SCHEMBL8881072 | 0.76 | GABRA1 (0.38) | — | |
| SCHEMBL8879602 | 0.74 | GABRA1 (0.39) | — | |
| SCHEMBL2809272 | 0.73 | PGK1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2807752 | 0.72 | PGK1 (0.35) | — | |
| SCHEMBL2807778 | 0.69 | TRPV1 (0.30) | — | |
| Bromide SCHEMBL2813570 | 0.69 | AMY1A (0.38) | — | |
| SCHEMBL2815631 | 0.69 | SETDB1 (0.31) | — | |
| Bromide SCHEMBL2810282 | 0.69 | NPC1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL2812693 | 0.68 | SETDB1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240713-A1 | AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2010-09-23 | — | — | US | disclosed |