SCHEMBL28101475

SCHEMBL28101475

O=C(O)C(O)C(OCCCCCCOC(C(=O)O)C(O)C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
PGD P52209 2/20 0.35
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
PDE4A P27815 1/20 0.32
SLC1A3 P43003 3/20 0.31
SLC1A2 P43004 3/20 0.31
SLC1A1 P43005 3/20 0.31
GPR84 Q9NQS5 3/20 0.30
FFAR1 O14842 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990177 0.90 GPR84 (0.46) TSHRGPR84FFAR1
SCHEMBL27703732 0.90 GPR84 (0.46) TSHRGPR84FFAR1
SCHEMBL27681636 0.90 GPR84 (0.46) TSHRGPR84FFAR1
SCHEMBL7773504 0.90 GPR84 (0.46) TSHRGPR84FFAR1
SCHEMBL6120610 0.90 GPR84 (0.46) TSHRGPR84FFAR1
SCHEMBL14721767 0.87 RARB (0.41) PGDGPR84FFAR1BLM
SCHEMBL3463165 0.87 TSHR (0.36) TSHRPGDCYP2C9PDE4A
SCHEMBL2979038 0.85 ATM (0.41) TSHRPGDALDH1A1GPR84FFAR1
SCHEMBL1594019 0.85 TSHR (0.31) TSHRPGD
Phosphoric Acid SCHEMBL28622249 0.84 LPAR3 (0.44) GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106349089-A Method using tartrate-polybasic acid complex to extract and separate metoprolol enantiomer 湖南理工学院 2017-01-25 CN disclosed