Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL3743070 | 0.87 | SMN1; SMN2 (0.37) | TSHR | |
| SCHEMBL234927 | 0.87 | TSHR (0.39) | TSHRCYP2C9PDE4APGDOR51E2 | |
| SCHEMBL28101475 | 0.87 | TSHR (0.39) | TSHRCYP2C9PDE4APGD | |
| 1,4-Butanediol SCHEMBL3736478 | 0.85 | ACHE (0.33) | TSHRCYP2C9PGD | |
| Ethylene Glycol SCHEMBL3732641 | 0.85 | ATM (0.37) | TSHRPGD | |
| SCHEMBL3728703 | 0.82 | TSHR (0.43) | TSHR | |
| SCHEMBL3739748 | 0.82 | TSHR (0.43) | TSHR | |
| SCHEMBL2979038 | 0.82 | ATM (0.41) | TSHRPGD | |
| Di(Hydroxyethyl)Ether SCHEMBL3742226 | 0.81 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL3741933 | 0.80 | PGD (0.35) | TSHRCYP2C9PDE4APGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130718-A1 | Diols and Polyols | COGNIS IP MANAGEMENT GMBH (DE) | 2010-05-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130718-A1 | Diols and Polyols | DECR2, HCAR2, HSD17B12 | TSHR 4820/4885CYP2C9 532/4885PDE4A 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.