Phosphoric Acid

Phosphoric Acid

SCHEMBL28622249

CCCCCCCCCCCCCCOC(C(=O)O)C(O)C(=O)O.O=P(O)(O)O

nearest known ligand 0.44

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.44
LPAR1 Q92633 5/20 0.44
LPAR2 Q9HBW0 3/20 0.44
LPAR5 Q9H1C0 1/20 0.42
GPR84 Q9NQS5 3/20 0.41
FFAR1 O14842 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39
P2RY10 O00398 1/20 0.38
CETP P11597 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990177 0.93 GPR84 (0.46) GPR84FFAR1HCAR2
SCHEMBL6120610 0.93 GPR84 (0.46) GPR84FFAR1HCAR2
SCHEMBL27681636 0.93 GPR84 (0.46) GPR84FFAR1HCAR2
SCHEMBL27703732 0.93 GPR84 (0.46) GPR84FFAR1HCAR2
SCHEMBL7773504 0.93 GPR84 (0.46) GPR84FFAR1HCAR2
Phosphoric Acid SCHEMBL28919710 0.90 LPAR3 (0.50) LPAR3LPAR1LPAR2LPAR5HCAR2
SCHEMBL2979038 0.86 ATM (0.41) GPR84FFAR1HCAR2
SCHEMBL27720867 0.84 ATM (0.39) GPR84FFAR1HCAR2
SCHEMBL28101475 0.84 TSHR (0.39) GPR84FFAR1
SCHEMBL5718514 0.82 HCAR2 (0.48) GPR84FFAR1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214889-B Environment-friendly trace lubricating oil and preparation method thereof 湖南鸿福实业有限公司 2023-05-09 CN claimed
CN-113214889-B Environment-friendly trace lubricating oil and preparation method thereof 湖南鸿福实业有限公司 2023-05-09 CN disclosed
CN-113249156-A Environment-friendly trace lubricant and preparation method thereof 上海金兆节能科技有限公司 2021-08-13 CN disclosed