SCHEMBL28101685

SCHEMBL28101685

C=CCOc1ccc(CC(C)C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
ALDH1A1 P00352 10/20 0.38
CYP2D6 P10635 3/20 0.38
KDM4E B2RXH2 5/20 0.37
HPGD P15428 3/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 2/20 0.36
TSHR P16473 1/20 0.36
SLC22A1 O15245 1/20 0.36
CYP1A2 P05177 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854358 0.87 LMNA (0.52) LMNAALDH1A1CYP2D6KDM4EHPGD
SCHEMBL4523312 0.81 GAA (0.41) LMNAALDH1A1CYP2D6KDM4EHPGD
SCHEMBL20237268 0.78 MEN1 (0.45) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL8161827 0.76 SMN1; SMN2 (0.45) LMNAALDH1A1KDM4EHPGDMAPT
SCHEMBL30401497 0.76 ALDH1A1 (0.42) LMNAALDH1A1KDM4EHPGDMAPT
SCHEMBL6862682 0.76 ALOX15 (0.51) MAPTGABRA1GABRB2SMN1; SMN2
SCHEMBL9495861 0.76 ALDH1A1 (0.39) LMNAALDH1A1CYP2D6KDM4EHPGD
SCHEMBL8244836 0.75 CYP2D6 (0.49) ALDH1A1CYP2D6KDM4EHPGDMAPT
SCHEMBL11659885 0.75 ALDH1A1 (0.43) LMNAALDH1A1KDM4EHPGDMAPT
SCHEMBL4778778 0.75 ALDH1A1 (0.50) LMNAALDH1A1KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008178-A Organoleptic compounds 国际香料和香精公司 2016-10-12 CN claimed
CN-106008178-A Organoleptic compounds 国际香料和香精公司 2016-10-12 CN disclosed