Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | NT5E | P21589 | 2/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501737 | 0.96 | NT5E (0.63) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL19180617 | 0.88 | POLB (0.57) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL3207372 | 0.88 | NT5E (0.72) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL17117807 | 0.88 | NT5E (0.72) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL29808596 | 0.88 | NT5E (0.72) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL2883759 | 0.87 | NT5E (0.58) | POLBNT5EENPP1P2RY1 | |
| SCHEMBL345288 | 0.87 | NT5E (0.67) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL4820794 | 0.87 | NT5E (0.67) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL17117823 | 0.87 | NT5E (0.67) | POLBNT5EENPP1P2RY1P2RY2 | |
| SCHEMBL29400356 | 0.87 | NT5E (0.67) | POLBNT5EENPP1P2RY1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109554418-A | The enzyme' s catalysis of L- nucleic acid | 诺松制药股份公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-104379748-B | Enzymatic synthesis of L-nucleic acids | 诺松制药股份公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-105916992-A | Synthesis of L-nucleic acids by enzymes | 诺松制药股份公司 | 2016-08-31 | — | — | CN | disclosed |