SCHEMBL2883759

SCHEMBL2883759

O=P(O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)C[C@@H]1O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.58
▸ POLB P06746 2/20 0.56
▸ P2RY1 P47900 2/20 0.52
▸ ENPP1 P22413 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19180617 0.92 POLB (0.57) NT5EPOLBP2RY1ENPP1
SCHEMBL1069101 0.91 POLB (0.56) NT5EPOLBP2RY1ENPP1
SCHEMBL23501737 0.91 NT5E (0.63) NT5EPOLBP2RY1ENPP1
Triphosphate SCHEMBL28101757 0.87 POLB (0.61) NT5EPOLBP2RY1ENPP1
SCHEMBL1533826 0.87 POLB (0.65) NT5EPOLBP2RY1ENPP1
SCHEMBL1533828 0.87 POLB (0.65) NT5EPOLBP2RY1ENPP1
SCHEMBL20266303 0.86 POLB (0.64) NT5EPOLBP2RY1ENPP1
SCHEMBL10438039 0.84 PNP (0.64) —
SCHEMBL855722 0.84 PNP (0.64) —
SCHEMBL17117808 0.83 NT5E (0.69) NT5EPOLBP2RY1ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3199639-B1 NOVEL MEASUREMENT METHOD USING KINASE, AND COMPOSITION ASAHI KASEI PHARMA CORP (JP) 2020-12-30 — — EP disclosed
US-10472665-B2 Measuring method and composition using kinase ASAHI KASEI PHARMA CORPORATION (JP) 2019-11-12 — — US disclosed
US-20170306389-A1 NOVEL MEASURING METHOD AND COMPOSITION USING KINASE ASAHI KASEI PHARMA CORPORATION (JP) 2017-10-26 — — US disclosed
EP-3199639-A1 NOVEL MEASUREMENT METHOD USING KINASE, AND COMPOSITION Asahi Kasei Pharma Corporation (JP) 2017-08-02 — — EP disclosed
US-9365604-B2 Oligomer-nucleoside phosphate conjugates NEKTAR THERAPEUTICS (US) 2016-06-14 — — US disclosed
US-20140371168-A1 OLIGOMER-NUCLEOSIDE PHOSPHATE CONJUGATES NEKTAR THERAPEUTICS (US) 2014-12-18 — — US disclosed
US-8741858-B2 Oligomer-nucleoside phosphate conjugates NEKTAR THERAPEUTICS 2014-06-03 — — US disclosed
US-20100286084-A1 Oligomer-Nucleoside Phosphate Conjugates NEKTAR THERAPEUTICS (US) 2010-11-11 — — US disclosed
WO-2009042064-A2 OLIGOMER-NUCLEOSIDE PHOSPHATE CONJUGATES NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-04-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371168-A1 OLIGOMER-NUCLEOSIDE PHOSPHATE CONJUGATES ENTPD5, SLC29A2, SLC29A1 NT5E 24/4885POLB 638/4885P2RY1 158/4885
US-20100286084-A1 Oligomer-Nucleoside Phosphate Conjugates ENTPD5, SLC29A2, SLC29A1 NT5E 25/4885POLB 665/4885P2RY1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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