Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 7/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2840581 | 0.98 | QPCT (0.40) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL23122864 | 0.84 | QPCT (0.45) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL31143361 | 0.82 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL6008269 | 0.82 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL23123086 | 0.79 | QPCT (0.51) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL21373604 | 0.77 | QPCT (0.37) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL7021134 | 0.76 | QPCT (0.49) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2474515 | 0.76 | QPCT (0.60) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2457410 | 0.75 | PSMD11 (0.42) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2459933 | 0.75 | MAPT (0.37) | QPCTQPCTLMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110685-A2 | PYRIMDDINYL AND 1,3,5-TRIAZINYL BENZIMTOAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2010-09-30 | — | — | WO | claimed |
| WO-2010110685-A2 | PYRIMDDINYL AND 1,3,5-TRIAZINYL BENZIMTOAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2010-09-30 | — | — | WO | disclosed |