Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975674 | 0.84 | ALDH1A1 (0.43) | NPC1RAB9AMEN1KMT2AAPP | |
| SCHEMBL1446254 | 0.83 | HPGD (0.46) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL694220 | 0.81 | NPC1 (0.49) | NPC1RAB9AIDO1MAPTSLC6A4 | |
| SCHEMBL693903 | 0.81 | SCD (0.41) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL693190 | 0.75 | MRGPRX4 (0.51) | MAOBIDO1RXRARXRBSLC6A4 | |
| SCHEMBL6484199 | 0.75 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2HTTIDO1 | |
| SCHEMBL13321688 | 0.73 | MRGPRX4 (0.63) | CCR5NPC1RAB9AHPGDSLC6A4 | |
| SCHEMBL985802 | 0.73 | EGFR (0.47) | MAOBIDO1LMNA | |
| SCHEMBL694978 | 0.73 | HTR1A (0.48) | HTTMEN1KMT2AMAPTHPGD | |
| SCHEMBL5685334 | 0.72 | GRM4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-B | Cyano-quinoline derivatives | 天津和美生物技术有限公司 | 2016-09-07 | — | — | CN | claimed |