Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035376 | 0.86 | PSMB11 (0.57) | TGM2BCHELMNAEGFRPSMB11 | |
| SCHEMBL1381244 | 0.82 | TGM2 (0.59) | TGM2LMNAEGFRF13A1TGM1 | |
| SCHEMBL5043916 | 0.81 | TGM2 (0.63) | TGM2PKMCYP1A2CYP2C9EGFR | |
| SCHEMBL9864914 | 0.79 | TGM2 (0.59) | TGM2PKMLMNAEGFRSRC | |
| SCHEMBL5041890 | 0.79 | TGM2 (0.69) | TGM2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27801542 | 0.78 | TGM2 (0.58) | TGM2LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21834411 | 0.78 | TGM2 (0.58) | TGM2EGFRF13A1TGM1 | |
| SCHEMBL16053417 | 0.77 | TGM2 (0.64) | TGM2LMNAEGFRF13A1TGM1 | |
| SCHEMBL9865437 | 0.74 | TGM2 (0.58) | TGM2PKMLMNAEGFRF13A1 | |
| SCHEMBL12179325 | 0.74 | TGM2 (0.58) | TGM2PKMLMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008480-A | Quinazoline compound containing cinnamamide structure and preparation method and application thereof | 江西科技师范大学 | 2016-10-12 | — | — | CN | disclosed |