SCHEMBL28102756

SCHEMBL28102756

CC(C#N)CCC(=O)O.O=C(SS)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.37
GPR139 Q6DWJ6 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CPA3 P15088 1/20 0.35
LMNA P02545 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL161151 0.84 CA12 (0.48) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
SCHEMBL161152 0.82 NR4A2 (0.38) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
Benzoyl Peroxide SCHEMBL28131759 0.81 LMNA (0.52) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
Thiobenzoic Acid SCHEMBL28164247 0.81 NR4A2 (0.40) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
Thiobenzoic Acid SCHEMBL2354925 0.81 NR4A2 (0.40) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
Benzoic Acid SCHEMBL28684289 0.81 DAO (0.39) ALDH1A1TSHRLMNATDP1CTSL
Diphenylmethane SCHEMBL28288647 0.78 CPA3 (0.46) ALDH1A1CYP2C19CYP1A2CYP2D6TSHR
SCHEMBL4229223 0.78 NR4A2 (0.37) NR4A2ALDH1A1CYP2C19CYP1A2CYP2D6
SCHEMBL11580814 0.77 LIG1 (0.46) ALDH1A1CYP2C19CYP1A2CYP2D6LMNA
SCHEMBL35490 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177573-B A kind of quaternary ammonium salt-fluorine silica acrylic acid ester block copolymer and preparation method and application are in antimicrobial coating material 天津大学 2016-09-07 CN disclosed