Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CPA3 | P15088 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229227 | 0.89 | MEN1 (0.39) | ALDH1A1CYP2C19NFKB1MAPK1LMNA | |
| Thiobenzoic Acid SCHEMBL2354925 | 0.87 | NR4A2 (0.40) | NR4A2GAAALDH1A1CYP2D6CYP2C19 | |
| Thiobenzoic Acid SCHEMBL28164247 | 0.87 | NR4A2 (0.40) | NR4A2GAAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL161152 | 0.84 | NR4A2 (0.38) | NR4A2GAAALDH1A1CYP2D6CYP2C19 | |
| Thiobenzoic Acid SCHEMBL2370364 | 0.83 | KMT2A (0.39) | ALDH1A1KDM4EPOLBLMNA | |
| Benzoyl Peroxide SCHEMBL28131759 | 0.81 | LMNA (0.52) | NR4A2ALDH1A1CYP2D6CYP2C19CYP1A2 | |
| Thiobenzoic Acid SCHEMBL161151 | 0.81 | CA12 (0.48) | NR4A2GAAALDH1A1CYP2D6CYP2C19 | |
| Diphenylmethane SCHEMBL28288647 | 0.78 | CPA3 (0.46) | ALDH1A1CYP2D6CYP2C19CYP1A2TSHR | |
| SCHEMBL28102756 | 0.78 | NR4A2 (0.37) | NR4A2GAAALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL11580814 | 0.77 | LIG1 (0.46) | GAAALDH1A1CYP2D6CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563759-B | Graphene and nano-silver composite material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2022-11-25 | — | — | CN | claimed |
| CN-113563759-A | Graphene and nano-silver composite material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2021-10-29 | — | — | CN | claimed |
| CN-113563759-B | Graphene and nano-silver composite material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2022-11-25 | — | — | CN | disclosed |
| CN-113563759-A | Graphene and nano-silver composite material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2021-10-29 | — | — | CN | disclosed |
| US-20150240103-A1 | COMPOSITIONS FOR HIGH SPEED PRINTING OF CONDUCTIVE MATERIALS FOR ELECTRONIC CIRCUITRY TYPE APPLICATIONS AND METHODS RELATING THERETO | E. I. DU PONT DE NEMOURS AND COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-8084558-B2 | Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090305045-A1 | Preparation of Transition Metal Nanoparticles and Surfaces Modified with (CO)Polymers Synthesized by RAFT | MCCORMICK III CHARLES L | 2009-12-10 | — | — | US | disclosed |
| US-7417096-B2 | Preparation of transition metal nanoparticles and surfaces modified with (CO) polymers synthesized by RAFT | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2008-08-26 | — | — | US | disclosed |
| US-7402690-B2 | Chain transfer agents for raft polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2008-07-22 | — | — | US | disclosed |
| US-20070123670-A1 | Chain transfer agents for raft polymerization in aqueous media | MCCORMICK CHARLES L | 2007-05-31 | — | — | US | disclosed |
| US-7186786-B2 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2007-03-06 | — | — | US | disclosed |
| US-7179872-B2 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2007-02-20 | — | — | US | disclosed |
| US-7138468-B2 | Preparation of transition metal nanoparticles and surfaces modified with (CO)polymers synthesized by RAFT | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2006-11-21 | — | — | US | disclosed |
| US-20060111531-A1 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2006-05-25 | — | — | US | disclosed |
| US-20060111532-A1 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2006-05-25 | — | — | US | disclosed |
| US-6855840-B2 | Chain transfer agents for raft polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2005-02-15 | — | — | US | disclosed |
| US-20030199653-A1 | Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2003-10-23 | — | — | US | disclosed |
| US-20030195310-A1 | Chain transfer agents for raft polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2003-10-16 | — | — | US | disclosed |
| US-20030191262-A1 | Chain transfer agents for raft polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2003-10-09 | — | — | US | disclosed |
| WO-2003066685-A2 | CHAIN TRANSFER AGENTS FOR RAFT POLYMERIZATION IN AQUEOUS MEDIA | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195310-A1 | Chain transfer agents for raft polymerization in aqueous media | TRRAP, NEFM, TMT1A | NR4A2 4486/4885GAA 2993/4885ALDH1A1 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.